Proteomics

Dataset Information

0

Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells


ABSTRACT: SARS-CoV-2 has caused the largest known coronavirus pandemic and is believed to have emerged from insectivorous bats. Little is known about the evolution of these viruses in their reservoir bat species. In this study, we investigated SARS-CoV-2-host interaction using human and bat cells. Bat cells mount a robust and early antiviral response but elicit a dampened pro-inflammatory response upon SARS-CoV-2 infection compared to human cells.

INSTRUMENT(S): maXis

ORGANISM(S): Homo Sapiens (human) Severe Acute Respiratory Syndrome Coronavirus 2 Eptesicus Fuscus

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Covid-19

SUBMITTER: Yoan Machado  

LAB HEAD: Arinjay Banerjee

PROVIDER: PXD058807 | Pride | 2025-06-05

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Calu3_24h_1_C2_1_273.d.zip Other
Calu3_24h_2_C5_1_285.d.zip Other
Calu3_24h_3_C8_1_297.d.zip Other
Calu3_24h_4_C11_1_309.d.zip Other
Calu3_24h_Mock1_C1_1_270.d.zip Other
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