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Protein interaction partners of C. elegans cap-specific mRNA (nucleoside-2'-O-)-methyltransferases CMTr-1 and CMTR-2.

ABSTRACT: RNA epigenetic modification at cap-adjacent 2’-O-ribose methylation (cOMe), which occurs on the first and second transcribed nucleotides of RNAs is highly conserved and is catalysed by the cap-adjacent methyltransferases CMTr1 and CMTR2 and We are studying CMTr-1 and CMTr-2 in C. elegans. Immunoprecipitation of endogenous, GFP-tagged CMTr-1 and CMTR-2 proteins reveal that CMTr-1 affinity purifies with splicing factors, RNA processing factors and RNA binding proteins.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Caenorhabditis Elegans

TISSUE(S): Embryo

SUBMITTER: Berndt Muller

LAB HEAD: Berndt Muller

PROVIDER: PXD058991 | Pride | 2025-04-30

REPOSITORIES: Pride

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			Action	DRS
	PE1001_CMTr1.zip	Other
	PE1001_CMTr1_CTRL1.raw	Raw
	PE1001_CMTr1_CTRL2.raw	Raw
	PE1001_CMTr1_CTRL3.raw	Raw
	PE1001_CMTr1_CTRL4.raw	Raw

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