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Comparative proteomic analysis for a putative glucose-1-phosphate thymidylyltransferase in Acidovorax citrulli

ABSTRACT: - Identification of proteins whose expression was affected by a putative glucose-1-phosphate thymidylyltransferase in Acidovorax citrulli str. KACC17005 - Shotgun proteomic analysis was used - Two strains were used with three biological replicates (total 6 samples). W: the wild-type strain. 2A: a putative glucose-1-phosphate thymidylyltransferase knockout mutant

INSTRUMENT(S):

ORGANISM(S): Acidovorax Citrulli

TISSUE(S): Cell Culture

SUBMITTER: Sang-Wook Han

LAB HEAD: Sang-Wook Han

PROVIDER: PXD059196 | Pride | 2026-02-09

REPOSITORIES: Pride

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			Action	DRS
	2A1_JH.msf	Msf
	2A1_JH.raw	Raw
	2A2_JH.msf	Msf
	2A2_JH.raw	Raw
	2A3_JH.msf	Msf

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Publications

A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.

Choi Junhyeok J Lee Suhyun S Kim Dohyun D Han Yoobin Y Rhyu Haerim H Lee Jisun H J JHJ Han Sang-Wook SW

Frontiers in plant science 20250521

Glucose-1-phosphate thymidylyltransferase (GptT) is crucial for bacterial cell wall/membrane functions. However, its roles in Acidovorax citrulli (Ac), the causative agent of bacterial fruit blotch (BFB) in watermelon, remain poorly understood. In this study, the roles of GptT in Ac (GptTAc) were elucidated through proteomic and phenotypic analyses using a mutant lacking GptTAc. The virulence of the mutant was remarkably reduced in the germinated-seed inoculation and leaf in ...[more]

PMID: 40470362

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