Proteomics

Dataset Information

0

Extracellular vesicles released by Naegleria fowleri


ABSTRACT: We have isolated and characterized the extracellular vesicles released by Naegleria fowleri (ATCC 30808) and determined their effect on MDCK cells and erythrocytes.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Naegleria Fowleri

SUBMITTER: Ismael Castelan-Ramírez  

LAB HEAD: Dra. Maritza Omaña Molina

PROVIDER: PXD059563 | Pride | 2025-05-07

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20241121_801_NF_IA_final_peptide.csv Csv
20241121_801_NF_IA_final_protein.csv Csv
CHRO001.rar Other
CHRO002.rar Other
CHRO003.rar Other
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Publications

Advances in the study of extracellular vesicles of Naegleria fowleri and their role in contact-independent pathogenic mechanisms.

Castelan-Ramírez Ismael I   Flores-Maldonado Catalina C   Hernández-Martínez Dolores D   Salazar-Villatoro Lizbeth L   Saucedo-Campos Alberto Daniel AD   Segura-Cobos David D   Méndez-Cruz Adolfo René AR   Omaña-Molina Maritza M  

Parasites & vectors 20250501 1


<h4>Background</h4>Extracellular vesicles (EVs) are spherical membrane particles released by prokaryotic and eukaryotic cells. EVs produced by pathogenic organisms are known to play a role in host-pathogen interactions; however, despite some reports on Naegleria fowleri EVs, their potential role in inducing cytopathic effects remains poorly understood. In this study, we evaluated the role of N. fowleri EVs in contact-independent pathogenic mechanisms.<h4>Methods</h4>Extracellular vesicles were c  ...[more]

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