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Deciphering the proteomic profile of the parasite Fasciola hepatica during host migration reveals new insights into early-stage infection

ABSTRACT: The project presents an in vivo mouse model coupled with quantitative SWATH-MS proteomics to study the early stages of Fasciola hepatica migration, focusing on the parasite's passage through the intestinal barrier to peritoneum(24 hours post-infection) and migration to the liver parenchyma (8 days post-infection). This approach aims to assess the proteomic changes in the parasite during these critical stages of infection.

INSTRUMENT(S): TripleTOF 6600

ORGANISM(S): Fasciola Hepatica (liver Fluke)

SUBMITTER: Marta López-García

LAB HEAD: Mar Siles-Lucas

PROVIDER: PXD059684 | Pride | 2025-06-05

REPOSITORIES: Pride

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			Action	DRS
	Fh24h_S1.wiff	Wiff
	Fh24h_S1.wiff.scan	Wiff
	Fh24h_S2.wiff	Wiff
	Fh24h_S2.wiff.scan	Wiff
	Fh24h_S3.wiff	Wiff

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Translation factor eIF5A controls mitochondrial protein import through the translation regulation of the mitochondrial inner membrane translocase receptor Tim50

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2024-10-23 | PXD043905 | Pride

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2025-01-23 | PXD056472 | Pride

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2025-05-07 | PXD056424 | Pride

2. Proteomic Insights into Seminal Plasma and Spermatozoa of Small-Spotted Catsharks (Scyliorhinus canicula): Differential expression analysis

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2023-09-07 | PXD043759 | Pride

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