Stoichiometric organisation of necrosome

ABSTRACT: The necrosome is a key macromolecular platform that initiates the RIPK1/RIPK3-dependent programme of cell death, termed necroptosis. Necroptosis plays an important role in controlling inflammation and cell death in multicellular organisms. Here, we used quantitative mass spectrometry to decipher the composition of the CD95L/BV6-induced necrosome.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell

DISEASE(S): Disease Free

SUBMITTER: Thilo Kaehne  

LAB HEAD: Prof. Dr. Thilo Kaehne

PROVIDER: PXD059873 | Pride | 2025-03-06

REPOSITORIES: Pride