Dataset Information
Adiponectin influences the behavior of stem cells in hormone-resistant breast cancer
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Breast Cancer
SUBMITTER: 
Marco Gaspari
LAB HEAD: Marco Gaspari
PROVIDER: PXD059964 | Pride | 2025-05-07
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| MCF7_TR_A5_2.raw | Raw | |||
| MCF7_TR_A5_3.raw | Raw | |||
| MCF7_TR_A5_4.raw | Raw | |||
| MCF7_TR_C2.raw | Raw | |||
| MCF7_TR_C3.raw | Raw |
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Publications
Adiponectin Influences the Behavior of Stem Cells in Hormone-Resistant Breast Cancer.
Cells 20250215 4
In the breast tumor microenvironment (TME), adipocytes exert a selective pressure on the behavior of breast cancer stem cells (BCSCs), which are involved in endocrine therapy resistance. In obesity, adipocytes secrete reduced levels of adiponectin, which promotes the growth and progression of ERα-positive breast cancer (BC). Here, we examined how low adiponectin levels affect the enrichment of the BCSC subpopulation and the mechanisms contributing to the maintenance of endocrine therapy resistan ...[more]
