Phosphoproteomic analysis of hypothalamic GT1-7 neurons

ABSTRACT: To elucidate the mechanism of neuronal activation, we conducted a global quantitative phosphoproteomic analysis of hypothalamic neurons treated with Raptin or PBS. By COG analysis of the differentially expressed phosphorylation protein, we found obvious alterations of transport and catabolism, as well as cell motility. By conducting a KEGG analysis using phosphoproteomic data, we identified the PI3K-AKT pathway.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture

SUBMITTER: Hui Peng  

LAB HEAD: Xianghang Luo

PROVIDER: PXD059980 | Pride | 2025-01-27

REPOSITORIES: Pride