Ferroptosis-armed dendritic cell vaccines for glioma immunotherapy

ABSTRACT: The type of cell death has proven to play a crucial role in cancer immunotherapy efficacy. Immunogenic cell death (ICD) enhances tumor adjuvanticity and antigenicity by releasing danger signals and altering the immune peptidome. The immunogenicity of ferroptosis, an iron-dependent form of cell death, remains uncertain. Proteomic analysis was performed to determine the proteomic changes in the lysate of cells killed by ferroptosis.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Glioma Cell

SUBMITTER: Evy Timmerman  

LAB HEAD: Dmitri V.

PROVIDER: PXD060116 | Pride | 2026-03-17

REPOSITORIES: Pride