Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Myoblast Development, Bone Marrow
SUBMITTER:
Animesh Sharma
LAB HEAD: Lars Hagen
PROVIDER: PXD060117 | Pride | 2025-11-10
REPOSITORIES: Pride
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Lamsal Apsana A Andersen Sonja Benedikte SB Nonstad Unni U Kurganovs Natalie Jayne NJ Skipworth Richard Je RJ Bjørkøy Geir G Pettersen Kristine K
Cancer & metabolism 20250605 1
<h4>Background</h4>Despite decades of efforts to find successful treatment approaches, cachexia remains a major unmet medical need. This condition, that affects patients with diverse underlying conditions, is characterized by severe muscle loss and is associated with reduced quality of life and limited survival. Search for underlying mechanisms that may guide cachexia treatment has mainly evolved around potential atrophy-inducing roles of inflammatory mediators, and in cancer patients, tumor-der ...[more]