Mouse NIH-3T3 cohesin TurboID LC-MSMS

ABSTRACT: The cohesin complex is a plieotropic regulator of genome structure and function. It is known to play a role in sister chromatin cohesin, DNA replication, DNA repair, and regulation of gene expression. Cohesin has several known interacting proteins that aid in the various roles within a nucleus, yet a comprehensive cohesin interactome has yet to be established. In this study, we utilized the biotin proximity ligation assay TurboID followed by LC-MS/MS in NIH-3T3 mouse fibroblast cells to identify novel proteins that interact with the cohesin complex.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Fibroblast

SUBMITTER: Natalie Rittenhouse  

LAB HEAD: Jill M. Dowen

PROVIDER: PXD060289 | Pride | 2025-06-02

REPOSITORIES: Pride