Proteomics

Dataset Information

Comparative analysis of platelet-derived extracellular vesicles protein extraction methodologies for mass spectrometry 


ABSTRACT: This study presents a comparative study of different methodologies for the extraction of proteins from platelet derived-extracellular vesicles (pEV) prior to subsequent mass spectrometry (MS) analysis. Protein isolation is performed through three different methodologies based on SDS-polyacrylamide gel electrophoresis (SDS-PAGE), organic solvent precipitation (OSP) or magnetic beads (MB), followed by protein digestion and sample acquisition by LC-MS/MS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Platelet

SUBMITTER: Carmen Raez Meseguer  

LAB HEAD: Joana Maria Ramis Morey

PROVIDER: PXD060357 | Pride | 2025-08-25

REPOSITORIES: Pride

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