Quantitative proteomics of brown bear muscle during hibernation

ABSTRACT: During hibernation, the physiology of bears is characterized by strong metabolic depression. In skeletal muscles, lipids are used as the main energy fuels although their oxidation rate is reduced, and glycolysis appears maintained likely feeding the Cori cycle. For a better knowledge on proteome remodelling during hibernation, this study analysed the bear (Ursus arctos) skeletal muscle proteome using shotgun proteomics to compare hibernation to the summer-active period.

INSTRUMENT(S):

ORGANISM(S): Ursus Arctos (brown Bear) (grizzly Bear)

TISSUE(S): Skeletal Muscle

SUBMITTER: Fabrice BERTILE  

LAB HEAD: Sarah Cianferani

PROVIDER: PXD060503 | Pride | 2026-03-02

REPOSITORIES: Pride