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Identification of RNA-mediated interaction partners of endogenous IGF2BP3 in HCT116 cells in control and ER stress conditions

ABSTRACT: IGF2BP3 is an RNA-binding protein that regulates mRNA stability, translation, and localization. IGF2BP3 binds to mRNAs encoding endoplasmic reticulum (ER) stress response proteins. To understand molecular mechanisms of its function we performed co-immunoprecipitation of the endogenous IGF2BP3 from colorectal carcinoma cell line HCT116 in control and ER stress conditions. RNase treatment was performed during washes to reveal RNA-bridged interactors.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Markus Hartl

LAB HEAD: Dr Gülsün Elif Karagöz

PROVIDER: PXD060548 | Pride | 2026-07-24

REPOSITORIES: Pride

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			Action	DRS
	20250110_Eclipse_NEO1_Anisimova_Karagoez_MPL_MUW_MPLID25003_DMSO_IGF2BP3RNase_1_s7_10p.raw	Raw
	20250110_Eclipse_NEO1_Anisimova_Karagoez_MPL_MUW_MPLID25003_DMSO_IGF2BP3RNase_2_s8_10p.raw	Raw
	20250110_Eclipse_NEO1_Anisimova_Karagoez_MPL_MUW_MPLID25003_DMSO_IGF2BP3RNase_3_s9_10p.raw	Raw
	20250110_Eclipse_NEO1_Anisimova_Karagoez_MPL_MUW_MPLID25003_DMSO_IGF2BP3_1_s4_10p.raw	Raw
	20250110_Eclipse_NEO1_Anisimova_Karagoez_MPL_MUW_MPLID25003_DMSO_IGF2BP3_2_s5_10p.raw	Raw

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