Proteomics

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Proteomic profiling of the global protein changes of GFP-NCL expressing HEK293T cells treated with NCL-ZATAC#20 or control.

ABSTRACT: We conducted unbiased mass spectrometric experiments to evaluate the specificity of NCL-ZATAC#20. In these studies, HEK293T cells expressing GFP-NCL were treated with NCL-ZATAC#20. The result revealed the detection of more than 6000 proteins, among which there was a notable degradation of GFP-NCL, confirming the targeted action of NCL-ZATAC#20 against NCL protein.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hek-293t Cell, Epithelial Cell

SUBMITTER: Songbo Xie  

LAB HEAD: Songbo Xie

PROVIDER: PXD060634 | Pride | 2025-03-04

REPOSITORIES: Pride

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Dataset's files

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Action DRS
Protac-Ctrol-first-pass.gg-matrix.tsv Tabular
Protac-Ctrol-first-pass.pg-matrix.tsv Tabular
Protac-Ctrol-first-pass.pr-matrix.tsv Tabular
Protac-Ctrol-first-pass.stats.tsv Tabular
Protac-Ctrol-first-pass.tsv Tabular
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