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4D label-free quantitative proteomic analysis of 9 rat condylar cartilage samples (n=3)

ABSTRACT: To determine the effect of different mechanical stresses on protein expression in condylar cartilage, we carried out 4D label-free quantitative proteomic analysis of condylar cartilage samples from the control (CON), 0.5 mm (0.5) and 1.5 mm (1.5) groups.

INSTRUMENT(S):

ORGANISM(S): Rattus Rattus (black Rat)

TISSUE(S): Cartilage

SUBMITTER: Wei Geng

LAB HEAD: Wei Geng

PROVIDER: PXD060931 | Pride | 2026-02-09

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	XA02078LQ_CON_1.raw	Raw
	XA02078LQ_CON_2.raw	Raw
	XA02078LQ_CON_3.raw	Raw
	XA02078LQ_T05_1.raw	Raw
	XA02078LQ_T05_2.raw	Raw

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1 - 5 of 10

Publications

Roles of VWA1 and Rac2 in compensatory and decompensatory responses via FGF9/FGFR3 and p38 MAPK signaling pathways in condylar chondrocytes under distinct mechanical stress.

Liu Yuqi Y Jia Fangwen F Li Kangya K Liang Chao C Li Yanxi Y Geng Wei W

Arthritis research & therapy 20250531 1

<h4>Background/purpose</h4>Few studies paid attention to compensatory and decompensatory responses of condylar cartilage under different mechanical conditions and the underlying mechanism.<h4>Materials and methods</h4>Compensatory and decompensatory models were established. In vivo compensatory (0.5 mm occlusal elevation) and decompensatory (1.5 mm elevation) models were established in rats using zirconia occlusal plates. Parallel in vitro models subjected condylar chondrocytes to physiological ...[more]

PMID: 40450276

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