Proteomics

Dataset Information

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Oesophageal Tumour and Normal Oesophageal and Stomach tissue HLA class II Immunopeptidomics

ABSTRACT: Oesophageal TumOesophageal Tumour and Normal Oesophageal and Stomach tissue were analysed with HLA class II Immunopeptidomics using the L243 antibody

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Stomach, Esophagus

SUBMITTER: Nicola Ternette  

LAB HEAD: Nicola Ternette

PROVIDER: PXD060958 | Pride | 2026-06-08

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
Experimental_design.csv Csv
FL1006_IPP110_RP_0037_373026_Normal_C2_2.csv Csv
FL1006_IPP110_RP_0037_373026_Normal_C2_even_2.raw Raw
FL1006_IPP110_RP_0037_373026_Normal_C2_odd_2.raw Raw
FL1006_IPP110_RP_0037_373029_Tumour_C2_1.csv Csv
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Publications

NetMHCIIphosPan: A Machine Learning Tool for Predicting HLA Class II Antigen Presentation of Phosphorylated Peptides.

Garcia Alvarez Heli M HM   Kaabinejadian Saghar S   Yari Hooman H   Shepherd Chloe M CM   Hildebrand William H WH   Sette Alessandro A   Peters Bjoern B   Parker Robert R   Ternette Nicola N   Nielsen Morten M  

Journal of proteome research 20260417 5

Phosphorylated peptides presented by human leukocyte antigen (HLA) class II molecules play pivotal roles in immune regulation, yet their characterization and prediction remain challenging due to data noise and limited HLA coverage. Here, we introduce NetMHCIIphosPan, a prediction method for HLA-II antigen presentation of phosphorylated peptides, developed using mass spectrometry (MS)-based immunopeptidomics data sets. Employing a refined peptide identification workflow, we reanalyzed earlier HLA  ...[more]

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