Queuosine-modified tRNA influences differentiation of Leishmania mexicana by codon bias translation

ABSTRACT: Using quantitative proteomics, we aim to compare the total proteome of L. mexicana wild (WT), knock-out (KO) and addback. The protein profile of all three will be related at five separate time points of life cycle differentiation. The objective is to elucidate the impact of Q-tRNA depletion on cellular proteome during differentiation.

INSTRUMENT(S):

ORGANISM(S): Leishmania Mexicana

SUBMITTER: Pavel Roudnický  

LAB HEAD: Zbynek Zdrahal

PROVIDER: PXD061534 | Pride | 2026-06-03

REPOSITORIES: Pride