Short-chain fatty acids synergistically interact with doxorubicin against gastric adenocarcinoma cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
DISEASE(S): Stomach Cancer
SUBMITTER: 
Muhammad Alsherbiny
LAB HEAD: Deep Bhuyan
PROVIDER: PXD061824 | Pride | 2026-01-19
REPOSITORIES: Pride
Dataset's files
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Publications
Postbiotics Combination Synergises the Antiproliferative Effects of Doxorubicin in Gastric Cancer Cells: A Cellular and Molecular Deep Dive.
Eladwy Radwa A RA Fares Mohamed M Alsherbiny Muhammad A MA Chang Dennis D Li Chun-Guang CG Bhuyan Deep Jyoti DJ
International journal of molecular sciences 20251229 1
Short-chain fatty acids (SCFAs) acetate, propionate, and butyrate are microbial metabolites with recognised roles in gut and immune homeostasis, but their therapeutic relevance in gastric cancer, particularly in combination with chemotherapeutics, remains unclear. This study investigated the antiproliferative synergy between a combined SCFA mixture (APB) and doxorubicin (Dox) in AGS gastric adenocarcinoma cells using integrated cellular, molecular, and proteomic approaches. APB and Dox each inhi ...[more]
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