Proteomics

Dataset Information

MS-based proteomics in HUVECs transfecting with IVT mRNA

ABSTRACT: The therapeutic success of in vitro-transcribed (IVT) mRNA depends on its stability and efficient translation. However, IVT mRNA is highly susceptible to immune-mediated degradation, limiting its efficacy. To investigate the binding protein profiles of IVT mRNA, we transfected HUVECs with 4SU-modified mRNA for 6h. LC-MS/MS was performed to identify the binding proteins of IVT mCherry mRNA.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Umbilical Vein Endothelium

SUBMITTER: Xing Peng  

LAB HEAD: Shu Meng

PROVIDER: PXD061961 | Pride | 2026-03-23

REPOSITORIES: Pride

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Dataset's files

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Action DRS
HUVECs.protein.quant.xlsx Xlsx
HUVECs_4SU.raw Raw
HUVECs_Control.raw Raw
PXD061961_community_annotated.sdrf.tsv Tabular
md5 Other
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