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Proteomic profiles of neutrophils from Behcet's uveitis patients and their sex differences

ABSTRACT: A label-free proteomic analysis was performed on peripheral blood neutrophils from active BU patients without medication and gender- and age-matched healthy controls

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Blood

DISEASE(S): Uveitis

SUBMITTER: Rong Liu

LAB HEAD: Peizeng Yang

PROVIDER: PXD062006 | Pride | 2025-12-29

REPOSITORIES: Pride

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			Action	DRS
	BP20230822-FB1.d.zip	Other
	BP20230822-FB2.d.zip	Other
	BP20230822-FB3.d.zip	Other
	BP20230822-FH1.d.zip	Other
	BP20230822-FH2.d.zip	Other

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Publications

Proteomic Profiles of Neutrophils from Behcet's Uveitis Patients and their Sex Differences.

Liu Rong R Wang Qingfeng Q Jiang Qingyan Q Chang Rui R Zhou Yan Y Ye Xingsheng X Luo Xiang X Lai Yujie Y Su Guannan G Yang Peizeng P

Inflammation 20250422 6

Behcet's uveitis (BU) is one of the most vision-threatening uveitis entities with male-biased incidence and severity. Neutrophil dysfunction has been implicated in the pathogenesis of this disease. However, their proteomic changes are not completely understood. We performed proteomic analysis on peripheral neutrophils from patients with active BU and identified 82 up-regulated and 516 down-regulated differentially expressed proteins (DEPs) compared to healthy controls (HCs). We further performed ...[more]

PMID: 40263198

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