Dataset Information

Proteome of the six eyes sand-spider Sicarius thomisoides venom

ABSTRACT: The six-eyed sand spider, Sicarius thomisoides, belongs to the Sicariidae family, whose venoms have recently been recognized for having a high toxic potential, similar to what has been demonstrated for the venom of spiders in the Loxosceles genus. However, with the exception of phospholipase D toxins previously reported in the venom of several species of the genus Sicarius, it is unknown which additional protein components are part of the venom of these spiders. The aim of the project was to characterize the venom proteome of the Chilean spider Sicarius thomisoides. For this the complete venom of adult and nymphs specimens captured at the desert of Chile were collected through electrostimulation and subsequently subjected to liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis. The proteome data will be analyzed and deposited in a mass spectrometry proteomics database.

INSTRUMENT(S):

ORGANISM(S): Sicarius Thomisoides

SUBMITTER: Jenny Moon

LAB HEAD: Leonard Foster

PROVIDER: PXD062481 | Pride | 2025-11-10

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	DIA-NN.1_9_1.Setup.exe	Other
	Jorge_01_50ng_8-31-2024_Slot2-01_14027.d.1.dar	Other
	Jorge_Sicarius-1_moreSeq_uniprot_NCBI.zip	Other
	NCBI_Loxosceles_laeta.fasta	Fasta
	NCBI_Sicarius-thomisoides.fasta	Fasta

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Publications

Proteome Analysis of the Six-Eyed Sand-Spider Sicarius thomisoides Venom.

Arán-Sekul Tomás T San Francisco Juan J Rojas José J Moon Kyung-Mee KM Foster Leonard L Catalán Alejandro A

Toxins 20250928 10

Spiders of the Sicarius genera (Araneae: Sicariidae) are commonly known as six-eyed sand spiders. Of the species described in Latin America, the species S. thomisoides has previously been shown to possess venom with a toxic potential comparable to that observed in the venom of the spider L. laeta. Although identifying the phospholipase D activity in the venom of S. thomisoides, it is still unknown what other components are part of the venom. In this study, we describe ...[more]

PMID: 41150187

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Dataset Information

Proteome of the six eyes sand-spider Sicarius thomisoides venom

Dataset's files

Publications

Proteome Analysis of the Six-Eyed Sand-Spider <i>Sicarius thomisoides</i> Venom.

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Dataset Information

Proteome of the six eyes sand-spider Sicarius thomisoides venom

Dataset's files

Publications

Proteome Analysis of the Six-Eyed Sand-Spider &lt;i&gt;Sicarius thomisoides&lt;/i&gt; Venom.

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OmicsDI is part of the ELIXIR infrastructure

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Proteome Analysis of the Six-Eyed Sand-Spider <i>Sicarius thomisoides</i> Venom.