Proteomics

Dataset Information

0

Detection of the TDP-43 interactome in C57Bl/6J mouse cortex and cerebellum using LC-MSMS


ABSTRACT: TDP-43 is a primary pathogenic protein in both amyotrophic lateral sclerosis and frontotemporal dementia, but it’s accumulation and aggregation show regional variation, with abundant deposition in the cortex, and a much lower burden in the cerebellum. Here we use mass spectrometry analysis to compare the protein interactome of TDP-43 within the cortex and cerebellum of young healthy C57Bl/6J mice.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

SUBMITTER: Steven Lynham  

LAB HEAD: Dr Jacqueline Mitchell

PROVIDER: PXD062532 | Pride | 2026-01-16

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
PR596_TH2_1.msf Msf
PR596_TH2_1.raw Raw
PR596_TH2_1_RR.mzid Mzid
PR596_TH2_1_RR.mzid_PR596_TH2_1_RR.MGF Mzid
PR596_TH2_2.msf Msf
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