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Cell division protein CdpA organises and anchors the midcell ring in haloarchaea

ABSTRACT: Many archaea appear to divide through the coordinated activities of two FtsZ homologues (FtsZ1 and FtsZ2) and another bacterial cell division homologue (SepF), which are part of the midcell division ring. Here, we identify an additional protein (HVO_0739, renamed Cell Division Protein A, CdpA) that is required for normal cell division in Haloferax volcanii, with homologues in other Haloarchaea. Protein localization and dynamics analyses, protein domain function studies, pull-down assays, and multimer structure predictions suggest that CdpA is part of a membrane complex that tethers FtsZ2 and other division proteins to the midcell membrane.

INSTRUMENT(S):

ORGANISM(S): Haloferax Volcanii Ds2

SUBMITTER: Iain Duggin

LAB HEAD: Iain Duggin

PROVIDER: PXD062651 | Pride | 2025-05-31

REPOSITORIES: Pride

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			Action	DRS
	CDPA_HA_01.raw	Raw
	CDPA_HA_02.raw	Raw
	CDPA_HA_03.raw	Raw
	CDPA_HA_04.raw	Raw
	CDPA_HA_05.raw	Raw

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