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Association of heme-bound HRI with S-DELE1 promotes HRI auto-phosphorylation

ABSTRACT: This dataset assesses the effects of S-DELE1 association on the auto-phosphorylation of human, heme-bound HRI. Human HRI and DELE1 were expressed in EIF2alpha-phospho-resistant cells supplemented with hemin. HRI was affinity purified, the elution subjected to denaturing gel electrophoresis, and HRI phosphorylation was assessed by MS. The data set identifies S-DELE1 induced phosphorylation sites in the N-terminal domain of HRI, its two kinase domains, and the kinase insert.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Lara Rheinemann

LAB HEAD: Andreas Pichlmair

PROVIDER: PXD062916 | Pride | 2026-06-09

REPOSITORIES: Pride

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			Action	DRS
	MaxQuant_2.4.0.0.zip	Other
	V0088-01_S008167_HRI_solv_EV_1.raw	Raw
	V0088-01_S008168_HRI_solv_EV_2.raw	Raw
	V0088-01_S008169_HRI_solv_EV_3.raw	Raw
	V0088-01_S008170_HRI_solv_EV_4.raw	Raw

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