Dataset Information

Proteomics of cyanidin 3-O-galactoside to alleviate LPS-induced inflammatory response in mammary epithelial cells of dairy goats

ABSTRACT: An in vitro mastitis cell model was constructed by treating mammary epithelial cells of dairy goats with LPS and intervening with cyanidin 3-O-galactoside as a way, to elucidate and explore the key mechanisms involved in the process of inflammation alleviation by cyanidin 3-O-galactoside.

INSTRUMENT(S):

ORGANISM(S): Capra Hircus (goat)

TISSUE(S): Epithelial Cell, Mammary Gland

DISEASE(S): Mastitis

SUBMITTER: Feng Rui

LAB HEAD: Rui Feng

PROVIDER: PXD063072 | Pride | 2025-09-15

REPOSITORIES: Pride

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Publications

Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation.

Feng Rui R Guo Lin L Wang Fan F Zhang Qian Q Wang Guoyan G Huang Hefei H Du Wei W An Hong H Yang Yue Y Miao Henghui H Zheng Peng P Chu Tingting T Zhang Dengke D Yan Xiaoxue X Mi Xiaoyu X Ma Qian Q Gao Weilin W Li Yushan Y Li Song S Zhang Yong Y Zhu Zhenliang Z Wang Yu Y Liu Jun J Liu Xu X

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20250624 33

Mastitis poses a huge economic burden, with antibiotics treatment leading to drug residues and the emergence of bacterial resistance. Therefore, there is an urgent need to develop alternatives to antibiotics for the treatment of mastitis. Anthocyanins (ACN) have excellent anti-inflammatory properties. However, the key pathways of mastitis disease progression and the therapeutic effects of ACN on mastitis remain poorly understood. In this study, using cows, goats, and mice as animal models, the e ...[more]

PMID: 40552401

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