Proteomics

Dataset Information

0

Immunoprecipitation and Mass Spectrometry Reveals Interactors of CD11b


ABSTRACT: We aimed to identify CD11b-associated inhibitory receptors,that control phagocytosis when engaged by ligands expressed on cancer cells. CD11b was immunoprecipitated from mouse bone marrow-derived macrophages (BMDMs), and the associated proteins were analyzed using mass spectrometry. A few inhibitory receptors were identified in CD11b immunoprecipitates from wild-type BMDMs, but not from CD18 (the β2 subunit of Mac-1)-deficient BMDMs, which lack CD11b.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Macrophage

SUBMITTER: Jiaxin Li  

LAB HEAD: Jiaxin Li and Andre Veillette

PROVIDER: PXD063540 | Pride | 2025-09-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
IPCD11b.sf3 Other
VL_20171204_VEI_01.raw Raw
VL_20171204_VEI_03.raw Raw
VL_20171204_VEI_04.raw Raw
VL_20180227_VEI_01.raw Raw
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