Proteomics

Dataset Information

Structural analysis of the CSN complex to understand its inhibition mechanism


ABSTRACT: We performed interaction and structural analyses to unravel the molecular mechanisms underlying CSN inhibition. Various methods including Cryo-EM, quantitative mass spectrometry and biochemical assays have been employed to define inhibitor-induced interaction and structural changes of the CSN complex in vitro and in cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Clinton Yu  

LAB HEAD: Dr. Lan Huang

PROVIDER: PXD063822 | Pride | 2025-11-22

REPOSITORIES: pride

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