Profiling CTBP2’s genome-wide interactome in murine macrophages in resting state and during LPS-induced inflammation
Ontology highlight
ABSTRACT: We profiled the genome-wide interactome of the co-repressor C-terminal binding protein 2 (CTBP2) in primary murine macrophages (BMDM) in vehicle and LPS conditions after 3 h of stimulation. We find that CTBP2 interacts with the transcription factors NF-κB and AP-1 and forms a corepressor complex that involves KDM1A, the NuRD complex and other co-repressors.
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Macrophage
SUBMITTER:
Michael Wierer
LAB HEAD: Henriette Uhlenhaut
PROVIDER: PXD063850 | Pride | 2025-06-08
REPOSITORIES: Pride
ACCESS DATA