Proteomics

Dataset Information

0

Profiling CTBP2’s genome-wide interactome in murine macrophages in resting state and during LPS-induced inflammation


ABSTRACT: We profiled the genome-wide interactome of the co-repressor C-terminal binding protein 2 (CTBP2) in primary murine macrophages (BMDM) in vehicle and LPS conditions after 3 h of stimulation. We find that CTBP2 interacts with the transcription factors NF-κB and AP-1 and forms a corepressor complex that involves KDM1A, the NuRD complex and other co-repressors.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Macrophage

SUBMITTER: Michael Wierer  

LAB HEAD: Henriette Uhlenhaut

PROVIDER: PXD063850 | Pride | 2025-06-08

REPOSITORIES: Pride

Dataset's files

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Action DRS
experimental_design.txt Txt
mqpar.xml Xml
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