Proteomics

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The surfaceome of chondrogenic cells


ABSTRACT: Chondrogenesis, the process through which cartilage forms, has implications for cartilage repair and osteoarthritis (OA) management. In this study, we present the first comprehensive quantitative analysis of the surfaceome of chondrogenic cells using a well-established in vitro chondrogenic model. By employing glycocapture-assisted enrichment targeting sialic acid residues on surface proteins, combined with high-throughput shotgun mass spectrometry, we identified novel components of the chondrogenic cell surfaceome.

INSTRUMENT(S):

ORGANISM(S): Gallus Gallus (chicken)

TISSUE(S): Chondrocyte Development, Chondrocyte

DISEASE(S): Osteoarthritis

SUBMITTER: David Boocock  

LAB HEAD: David Boocock

PROVIDER: PXD064013 | Pride | 2026-01-19

REPOSITORIES: Pride

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Publications

Podocalyxin and ciliary neurotrophic factor receptor are novel components of the surfaceome of chondrogenic cells.

Kovács Patrik P   Brazda Peter P   Hajdú Tibor T   Harsányi Boglárka B   Juhász Krisztián K   Takács Roland R   Vágó Judit J   Wang Zhangzheng Z   Coveney Clare C   Boocock David J DJ   Matta Csaba C  

Cell communication and signaling : CCS 20251202 1


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