Human N-terminal proteome using TMPP labelling and dN-TOP approach

ABSTRACT: The present study describes the free N-terminome analysis of human mitochondria-enriched samples using trimethoxyphenylphosphonium (TMPP) labelling approaches and dN-TOP validation of the proteomics data acquired with an Orbitrap mass spectrometer. The doublet N-terminal oriented proteomics (dN-TOP) strategy is based on a double light/heavy TMPP labelling which enable fast, efficient and reliable high throughput N-terminome data validation

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Monocyte, Cell Culture

SUBMITTER: Magali Rompais  

LAB HEAD: Christine CARAPITO

PROVIDER: PXD064426 | Pride | 2026-03-23

REPOSITORIES: Pride