Proximity labeling of NF1 using APEX

ABSTRACT: The goal of the study was to profile protein interaction neighborhood of NF1 by expressing NF1-APEX and profiling biotinylated proteins in proximity of NF1. Interactions were assessed at basal conditions or in the context of MEK inhibition with selumetinib.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Peripheral Nervous System Neuron

DISEASE(S): Neurofibromatosis

SUBMITTER: Nadia Arang  

LAB HEAD: Harish Vasudevan

PROVIDER: PXD064557 | Pride | 2025-06-17

REPOSITORIES: Pride