Glycoproteomics of healthy and Fut8-KO mice platelet lysates
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Blood Platelet, Platelet
SUBMITTER: 
The Huong Chau
LAB HEAD: Morten Thaysen-Andersen
PROVIDER: PXD064579 | Pride | 2026-06-04
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 240517_OE_KC_PLT008_C1_E_2.raw | Raw | |||
| 240517_OE_KC_PLT008_C2_E_2.raw | Raw | |||
| 240517_OE_KC_PLT008_C3_E.raw | Raw | |||
| 240517_OE_KC_PLT008_K1_E.raw | Raw | |||
| 240517_OE_KC_PLT008_K2_E.raw | Raw |
Items per page: 5 1 - 5 of 12 |
Publications
FUT8-Dependent Core Fucosylation: Essential for Platelet Function and a Target in Thrombosis.
Yang Ruey-Bing RB Tu Cheng-Fen CF Chen Yan-Ting YT Chau The Huong TH Lin Shu-Wha SW Tsai Cheng-Da CD Li Fu-An FA Thaysen-Andersen Morten M Lin Yuh-Charn YC
Arteriosclerosis, thrombosis, and vascular biology 20260604
<h4>Background</h4>FUT8 (fucosyltransferase 8) adds core fucose to the innermost <i>N</i>-acetylglucosamine of <i>N</i>-glycans on surface receptors, affecting ligand binding and downstream signaling in various cellular contexts. Here, we examine the role of FUT8-catalyzed core fucosylation in platelet activity in vivo, and we evaluate the potential antithrombotic strategy of FUT8 inhibition.<h4>Methods</h4>To investigate whether the extracellular domains of platelet adhesion receptors are core ...[more]
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