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Mouse brain endothelial cells LC-MS/MS

ABSTRACT: In our study, we used immunofluorescence to examine brain endothelial cells (ECs) from Slc3a2 ECKO mice and found that blood-brain barrier markers, including tight junction proteins and transcytosis-associated proteins, exhibited significant changes compared to Slc3a2 WT mice. To further investigate these findings, we performed flow cytometry sorting on brain ECs from both Slc3a2 WT and ECKO mice. Subsequently, we conducted proteomic sequencing to identify additional molecular changes, particularly those related to blood-brain barrier markers.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain, Endothelial Cell

SUBMITTER: Shilun Yang

LAB HEAD: Junlei Chang

PROVIDER: PXD064613 | Pride | 2026-03-27

REPOSITORIES: Pride

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			Action	DRS
	20240911_190944_CQT2024080804-F001.sne	Other
	checksum.txt	Txt
	yisuan_CHI123_01_ECKO_1.raw	Raw
	yisuan_CHI123_02_WT_2.raw	Raw
	yisuan_CHI123_03_WT_3.raw	Raw

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