Proteomics

Dataset Information

Individual acute and rapid depletion of 55LCC-complex members

ABSTRACT: HCT116 Cells were CRISPR-Edited, selected and sub-cloned for homocygous endogenous tagged clones. SPATA5 (Q8NB90), SPATA5L1 (Q9BVQ7), CINP (Q9BW66) and C1ORF109 (Q9NX04) were tagged with FKBP12F36V and subjected to 50nM of dTAGV-1 PROTAC molecule or equimolar DMSO solvent control for the indicated times.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Colon

DISEASE(S): Colon Cancer

SUBMITTER: Jonas Walter  

LAB HEAD: Chunaram Choudhary

PROVIDER: PXD064619 | Pride | 2026-07-29

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
20240524_AST6_VanNeoMLN_JW_SA_DIA_HCT116_C1ORF109-dTAG_DMSO-6h_Exp1.raw Raw
20240524_AST6_VanNeoMLN_JW_SA_DIA_HCT116_C1ORF109-dTAG_DMSO-6h_Exp2.raw Raw
20240524_AST6_VanNeoMLN_JW_SA_DIA_HCT116_C1ORF109-dTAG_DMSO-6h_Exp3.raw Raw
20240524_AST6_VanNeoMLN_JW_SA_DIA_HCT116_C1ORF109-dTAG_V1-50nM-180min_Exp1.raw Raw
20240524_AST6_VanNeoMLN_JW_SA_DIA_HCT116_C1ORF109-dTAG_V1-50nM-180min_Exp2.raw Raw
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