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Individual acute depletion of 55LCC-complex members (SILAC-DDA)

ABSTRACT: HCT116 Cells were CRISPR-Edited, selected and sub-cloned for homocygous endogenous tagged clones. SPATA5 (Q8NB90), SPATA5L1 (Q9BVQ7), CINP (Q9BW66) and C1ORF109 (Q9NX04) were tagged with FKBP12F36V and subjected to 50nM of dTAGV-1 PROTAC molecule or equimolar DMSO solvent control for the indicated times.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

DISEASE(S): Colon Cancer

SUBMITTER: Jonas Walter

LAB HEAD: Chuna Ram Choudhary

PROVIDER: PXD064896 | Pride | 2026-07-29

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	20210709_Human_uniprot-proteome_UP000005640.fasta	Fasta
	20211119_Expl4_nLC1_JW_SA_SPATA5L1-dtag_ctrl-L_2hdtag50nM-M_6hdtag50nM6-H_JWD377_N1_F1.raw	Raw
	20211119_Expl4_nLC1_JW_SA_SPATA5L1-dtag_ctrl-L_2hdtag50nM-M_6hdtag50nM6-H_JWD377_N1_F10.raw	Raw
	20211119_Expl4_nLC1_JW_SA_SPATA5L1-dtag_ctrl-L_2hdtag50nM-M_6hdtag50nM6-H_JWD377_N1_F11.raw	Raw
	20211119_Expl4_nLC1_JW_SA_SPATA5L1-dtag_ctrl-L_2hdtag50nM-M_6hdtag50nM6-H_JWD377_N1_F12.raw	Raw

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