Proteomics

Dataset Information

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AP-MS Screening for novel Ribosome Biogenesis factors revealing 55LCC


ABSTRACT: Data from our initital screening for novel biogenesis factors in human ribosome biogenesis, revealing 55LCC interaction and interaction within 55LCC. Further, the dataset includes 55LCC depletion data trapping the pre-60S, enriching non-released biogenesis factors on the pre-60S. In addition transgene variants were tested and the dependency of SPATA5L1 ATPase activity for Ribosome-55LCC interaction via GTPBP4-FLAG silac interactome in the presence of dual ATPase dead mutant while endogen was depleted.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

DISEASE(S): Colon Cancer

SUBMITTER: Jonas Walter  

LAB HEAD: Chunaram Choudhary

PROVIDER: PXD065027 | Pride | 2026-07-29

REPOSITORIES: Pride

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