Proteomics

Dataset Information

0

Serum Proteome Analysis of IgA Nephropathy  


ABSTRACT: Proteome comparison between IgAN patients who progressed (PR) and those who remained stable (non-progressors, NP) before clinical divergence.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

DISEASE(S): Iga Glomerulonephritis

SUBMITTER: Niyaz Alsharabi  

LAB HEAD: Øystein Eikrem

PROVIDER: PXD065216 | Pride | 2026-02-09

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Jessica_F_IgG_Ex1_F.mzML Mzml
Jessica_F_IgG_Ex1_F.mzid Mzid
Jessica_F_IgG_Ex1_F1.raw Raw
Jessica_F_IgG_Ex1_F10.raw Raw
Jessica_F_IgG_Ex1_F2.raw Raw
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Publications

Serum proteome analysis detects early molecular signatures of disease progression in IgA nephropathy.

Chen Tony Jialiang TJ   Skandalou Eleni E   Fritz-Wallace Katarina K   Apeland Terje T   Knoop Thomas T   Marti Hans-Peter HP   Eikrem Øystein Ø   Furriol Jessica J  

Clinical kidney journal 20251111 12


<h4>Background</h4>Immunoglobulin A nephropathy (IgAN) is a common cause of chronic kidney disease (CKD) and identifying early molecular signatures is crucial for IgAN risk stratification and timely intervention. In this study we used serum proteomics to investigate molecular differences between IgAN patients who progressed and those who remained stable before separation in kidney function became apparent.<h4>Methods</h4>Serum samples from 40 adults with biopsy-proven IgAN were analysed and clas  ...[more]

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