Proteomics

Dataset Information

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Proteome integral solubility alteration assay for monitoring antibody-antigen interactions in cells


ABSTRACT: Proteome Integral Solubility Alteration (PISA) assay is normally used for characterization of the interactions between a small molecule and the cellular proteome. Here we modified PISA uniquely to identify the antigen (tumor necrosis factor alpha) in activated monocytes using the monoclonal antibody Infliximab.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Monocyte

SUBMITTER: Susanna Lundstrom  

LAB HEAD: Roman Zubarev

PROVIDER: PXD065457 | Pride | 2026-05-20

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20220728_05_PISA1.raw Raw
20220728_05_PISA3_tmt16_314599.msf Msf
20220728_07_PISA2.raw Raw
20220728_09_PISA3.raw Raw
20220905_54_PISA4_1.raw Raw
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