Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Malignant Cell, Kidney
DISEASE(S): Renal Cell Carcinoma
SUBMITTER:
Shuxia Liu
LAB HEAD: Shuxia Liu
PROVIDER: PXD065914 | Pride | 2025-11-03
REPOSITORIES: Pride
| Action | DRS | |||
|---|---|---|---|---|
| 769_P_peptides.xlsx | Xlsx | |||
| 769_P_proteins.xlsx | Xlsx | |||
| CAKI_1_peptides.xlsx | Xlsx | |||
| CAKI_1_proteins.xlsx | Xlsx | |||
| R20221001815_769_P.mgf | Mgf |
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The Journal of biological chemistry 20250916 11
Tripartite motif-containing 44 (TRIM44), a member of the TRIM protein family, has emerged as a regulator in multiple cancer types, yet its functional role and molecular mechanisms in clear cell renal cell carcinoma (ccRCC) remain poorly characterized. Here, we identified TRIM44 as a tumor suppressor in ccRCC through integrated clinical and functional analyses. Clinically, TRIM44 expression was significantly downregulated in ccRCC tissues compared with adjacent normal tissues, and its reduced exp ...[more]