Proteomics

Dataset Information

0

Extracellular Domain Shedding of TROP2 Activates EGFR Signaling to Drive Prostate Cancer Metastasis


ABSTRACT: Pull-down experiments were performed to characterize the interactome of the shed extracellular domain of TROP2 (TECD) in prostate cancer. Two independent strategies were used: (1) immunoprecipitation of TROP2 from patient sera, and (2) immunoprecipitation of DU145 cell lines treated with TECD. Proteins were analyzed by shotgun proteomics.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Prostate Cancer Cell Line

DISEASE(S): Prostate Cancer

SUBMITTER: Sharon Pitteri  

LAB HEAD: Sharon Pitteri

PROVIDER: PXD065965 | Pride | 2025-08-08

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
ECH_218_01.raw Raw
ECH_218_01.raw_20210106_Byonic_Gpeps.xlsx Xlsx
ECH_218_02.raw Raw
ECH_218_02.raw_20210106_Byonic_Gpeps.xlsx Xlsx
ECH_218_03.raw Raw
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