Proteomic profiling of PSMA-high and PSMA-low expressing regions from human prostate cancer tissues

ABSTRACT: This proteomics dataset comprises samples for comparative proteomic analyses of PSMA-heterogeneous prostate cancer tissues. The study aimed to characterize the proteomic differences between PSMA-high and PSMA-low expressing tumor regions within individual patients to better understand the biological role of PSMA in prostate cancer. Patients undergoing radical prostatectomy were selected based on pre-operative [68Ga]Ga-PSMA PET/MRI imaging that demonstrated primary tumor heterogeneity with distinct PSMA-high and PSMA-low regions and matched lymph node metastasis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Prostate Gland

DISEASE(S): Prostate Carcinoma

SUBMITTER: Markus Hartl  

LAB HEAD: Univ.-Prof. Mag. Dr. Gerda Egger

PROVIDER: PXD065989 | Pride | 2026-10-19

REPOSITORIES: Pride