ORF1p partners in dopaminergic neurons
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ABSTRACT: We and others have previously observed a widespread expression of ORF1p in mouse and human neurons at steady-state. This somewhat surprising presence of ORF1p in neurons evokes the question of a possible physiological role of ORF1p specific to these cells. To address this question, we used a quantitative mass spectrometry approach to identify protein partners of endogenous ORF1p in mouse (differentiated MN9D) and human (differentiated LUHMES) dopaminergic neurons using well characterized and specific antibodies to ORF1p.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)
TISSUE(S): Cell Culture
SUBMITTER:
Vanessa Masson
LAB HEAD: Damarys Loew
PROVIDER: PXD066047 | Pride | 2026-07-23
REPOSITORIES: Pride
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