Profiling pathogenesis stages of Ceratocystis manginecans infecting Acacia mangium using Tandem Mass Tag (TMT) quantitative proteomics
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ABSTRACT: This study investigates the molecular pathogenesis of Ceratocystis manginecans, a fungal pathogen responsible for wilt and canker disease in Acacia mangium. Using a TMT-based quantitative proteomics approach, protein expression was profiled at early stages (1 h and 24 h post-inoculation) following infection with two fungal isolates, CAM and CEP. A total of 205 proteins were identified, with 105 differentially expressed across conditions. The results highlight key virulence-related processes such as DNA repair, oxidative stress response, and host-specific metabolic adaptation. This dataset reveals valuable protein-protein interaction networks that underpin pathogenicity and may inform strategies for disease control in forest plantations.
INSTRUMENT(S):
ORGANISM(S): Ceratocystis Manginecans
SUBMITTER:
Samsuddin Ahmad Syazwan
LAB HEAD: Mansor Patahayah
PROVIDER: PXD066081 | Pride | 2025-12-18
REPOSITORIES: Pride
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