Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression

ABSTRACT: Histone acetylation is widely assumed to directly instruct gene activation. Among acetylated residues, H4K16ac is one of the most abundant modifications, conserved across all eukaryotes. Here we analyzed histone PTM profiles in MSL KO and HDAC inhibitor-treated cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Mammary Gland Epithelial Cell

SUBMITTER: Roberta Noberini  

LAB HEAD: Tiziana Bonaldi

PROVIDER: PXD066155 | Pride | 2025-09-29

REPOSITORIES: Pride