Species-specific regulation of necroptosis by STK38-dependent RIPK1 phosphorylation

ABSTRACT: we identify serine/threonine kinase 38 (STK38) as a novel direct RIPK1 activator. STK38 binds to RIPK1, integrates into RIPK1-containing death complexes, and promotes RIPK1-dependent cell death.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

SUBMITTER: Seongmi Kim  

LAB HEAD: Jaewhan Song

PROVIDER: PXD066201 | Pride | 2026-07-10

REPOSITORIES: Pride