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Hydroxyl Radical and Trifluoromethyl Carbohydrate Footprinting for Probing Protein Binding Components of Oligosaccharides

ABSTRACT: The NAG3 was modified by hydroxyl radicals and CF3 radicals and determined the end residues where these modifications occur.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Sandeep Misra

LAB HEAD: Joshu S. Sharp

PROVIDER: PXD066426 | Pride | 2025-09-29

REPOSITORIES: Pride

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			Action	DRS
	08-06-24-NAG3_IsomericGlycans_in_Lectin-0V.raw	Raw
	08-06-24-NAG3_IsomericGlycans_in_Lectin-0V.xlsx	Xlsx
	08-06-24-NAG3_IsomericGlycans_in_Lectin-900V-1.raw	Raw
	08-06-24-NAG3_IsomericGlycans_in_Lectin-900V-1.xlsx	Xlsx
	08-06-24-NAG3_IsomericGlycans_in_Lectin-900V-2.raw	Raw

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Hydroxyl and Trifluoromethyl Radical Carbohydrate Footprinting for Probing Protein Binding Components of Oligosaccharides.

Yusuph Quadrat Q Misra Sandeep K SK Liu Hao H Sharp Joshua S JS

bioRxiv : the preprint server for biology 20250510

Carbohydrates are found in various forms in living organisms, both as free-standing glycans as well as glycoconjugates including glycoproteins, glycolipids, and glycosaminoglycans. These structures play crucial roles in many biological processes, often mediated or influenced by interactions of carbohydrates with other biomolecules. However, studying these interactions is particularly challenging due to the structural complexity of carbohydrates, their dynamic conformational behavior, and the low ...[more]

PMID: 40654815

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