Proteomics

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Proteomic analysis of children with distinct eating timing pattern


ABSTRACT: This proteomics study investigates the molecular mechanisms underlying the relationship between eating timing patterns and cardiovascular health in children and adolescents. We performed comprehensive proteome profiling of plasma samples from 51 participants categorized into three distinct eating pattern groups: extended eating window, late eating window, and early eating window. The analysis revealed significant differences in protein expression patterns associated with metabolic regulation, inflammation, and cardiovascular function between these groups.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

SUBMITTER: Xiaohua Liang  

LAB HEAD: Xiaohua Liang

PROVIDER: PXD066466 | Pride | 2026-02-23

REPOSITORIES: Pride

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Publications

Multiomics insights into eating time patterns and cardiovascular risk among Chinese children.

Liu Qin Q   Chen Jingyu J   An Xizhou X   Chen Lanling L   Bai Bo B   Chen Lijing L   Huang Daochao D   Ma Jun J   Xiao Lun L   Yuan Shuanggui S   Li Jianxin J   Liang Xiaohua X  

Nature communications 20260121


As the prevalence of cardiovascular risk factors in children continues to rise globally, identifying modifiable lifestyle factors becomes increasingly important for early prevention. Here, using data from a large-scale cohort (2021-2024) involving 7459 Chinese children from three provinces, we examine the association between eating timing patterns and multiple cardiovascular parameters. Participants are classified into three eating patterns: extended eating window (duration more than 12.5 hours)  ...[more]

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