A New Family of Tubular Pilus from Microcystis aeruginosa, a Harmful Algal 2 Bloom Forming Cyanobacterium
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ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Microcystis Aeruginosa Pcc 7806sl
SUBMITTER: 
Peter Prevelige
LAB HEAD: Peter Prevelige
PROVIDER: PXD066594 | Pride | 2026-02-09
REPOSITORIES: Pride
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Publications
A family of tubular pili from harmful algal bloom forming cyanobacterium Microcystis aeruginosa.
Ricca John G JG Petersen Holly A HA Grosvirt-Dramen Adam A Mayali Xavier X Naylon Sarah H SH Duersch Bobby G BG Dufresne Craig P CP Weber Peter K PK Sonani Ravi R RR Prevelige Peter E PE Hochbaum Allon I AI Merk Vivian V Louda J W JW Wang Fengbin F
Nature communications 20250829 1
Cyanobacteria are vital photosynthetic prokaryotes, but some form harmful algal blooms (cyanoHABs) that disrupt ecosystems and produce toxins. The mechanisms by which these blooms form have yet to be fully understood, particularly the role of extracellular components. Here, we present a 2.4 Å cryo-EM structure of a pilus, termed the cyanobacterial tubular (CT) pilus, found in the cyanoHAB-forming Microcystis aeruginosa. The pilin exhibits a unique protein fold, forming a tubular pilus structure ...[more]
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