Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

DIA-based proteomic profiling of hCMECs infected with ExPEC RS218

ABSTRACT: Human cerebral microvascular endothelial cells (HCMECs) were infected with extraintestinal pathogenic Escherichia coli (ExPEC) strain RS218 at a multiplicity of infection (MOI) of 1 for 3 hours. Proteomic analysis was performed to evaluate host cellular responses. Infected samples were compared to uninfected controls (MOCK) to identify differentially expressed proteins associated with ExPEC infection.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Endothelial Cell

SUBMITTER: Zhiwei Li

LAB HEAD: Zhiwei Li

PROVIDER: PXD066627 | Pride | 2026-04-28

REPOSITORIES: Pride

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	README_Proteomics_RS218.txt	Txt
	YAS202312120059-1.pg_matrix.tsv	Tabular
	YAS202312120059-1.pr_matrix.tsv	Tabular
	YAS202312120059_1_MOCK_1.raw	Raw
	YAS202312120059_1_MOCK_2.raw	Raw

Items per page:

1 - 5 of 11

Similar Datasets

Dynamic transcriptome profiling of mouse spleen infected with extraintestinal pathogenic Escherichia coli

Project description:Extraintestinal pathogenic Escherichia coli (ExPEC) is a common bacterial strain causing diverse diseases in humans and animals. To analyse the detailed mechanisms underlying ExPEC-mediated sepsis in humans, the transcriptome response of mice at 3h,6h, and 12h after ExPEC infection was analyzed by RNA-seq of mouse spleen samples.

2022-11-11 | GSE140637 | GEO

Ribosome profiling of NIH-3T3 cells infected with MCMV

Project description:NIH-3T3 cells were infected with wildtype MCMV at a multiplicity of infection (MOI) of 10. Ribosome profiling was performed at the indicated times of infection as described in Rutkowski et al., Nature Communications 2015.

2020-08-07 | GSE102375 | GEO

Transcriptional profiling of extraintestinal Escherichia coli exposed to cranberry pomace extracts alone or in combination with ceftriaxone

Project description:To investigate the effects of ceftriaxone and cranberry pomace extract on transcriptome of extraintestinal E. coli (ExPEC)

2023-06-01 | GSE205240 | GEO

PAR-iCLIP MCMV infection

Project description:Swiss murine embryonic fibroblasts (NIH-3T3) or murine TCMK-1 epithelial cells were infected with BAC-derived wild-type Smith strain mouse cytomegalovirus (MCMV) at a multiplicity of infection (MOI) of 10. PAR-iCLIP was performed using 4-thiouridine labeling on both uninfected and MCMV-infected cells (72h post infection).

2025-07-05 | GSE207656 | GEO

Proteomics analysis of A549 cells infected with NDV

Project description:A549 cells were infected with NDV at a multiplicity of infection (MOI) of 3 at 37°C, and the cells were collected 24 hours post-infection.

2025-11-07 | PXD070444 |

Integrated Transcriptomics, Proteomics, and Metabolomics Analysis Reveals Newcastle Disease Virus Reshapes Glycerophospholipid Metabolism

Project description:<p _msttexthash='40138319' _msthash='348'>A549 cells were infected with NDV at a multiplicity of infection (MOI) of 3 at 37°C, and the cells were collected 24 hours post-infection.</p>

2025-11-05 | MTBLS13267 | MetaboLights

Human bronchial epithelial cell line Beas-2B

Project description:Human bronchial epithelial cell line Beas-2B were infected with Streptococcus pneumoniae at Multiplicity of Infection (MOI) of 0.5 and 1 or treated with lipoteichonic acid (LTA) for 9 and 16 h. The mRNA profile changes upon infection shall be determined to investigate Streptococci pathogenesis.

2023-02-01 | GSE195778 | GEO

Transcription start site profiling of HSV-1 infected cells using cRNA-seq and dRNA-seq

Project description:Primary human foreskin fibroblasts (HFF) were infected with wild-type simplex virus 1 (HSV-1) strain 17 at a multiplicity of infection (MOI) of 10. Sequencing libraries were prepared using the cRNA-seq and dRNA-seq protocol from the indicated time points of infection.

2020-04-07 | GSE128323 | GEO

Wide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling

Project description:Primary human foreskin fibroblasts (HFF) were infected with wild-type simplex virus 1 (HSV-1) strain 17 at a multiplicity of infection (MOI) of 10. Ribosome profiling was performed at various times during infection with minor modification to the protocol described in Stern-Ginossar N et al., Science 2012

2015-05-26 | GSE60040 | GEO

cRNA-seq of MCMV

Project description:Swiss murine embryonic fibroblasts (NIH-3T3) were infected with wild-type Smith strain mouse cytomegalovirus (MCMV) at a multiplicity of infection (MOI) of 10. Sequencing libraries were prepared using the cRNA-seq protocol from the indicated time points of infection as described by Whisnant A.W. et al, Nat. Commun (2020)

2023-04-26 | GSE212285 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data